Anti-ERBB2 Recombinant Antibody (Margetuximab) (CAT#: TAB-761)
Recombinant chimeric (mouse/human) antibody expressed in CHO binding to human ERBB2. Margetuximab is a monoclonal antibody designed for the treatment of cancer.
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SPR
Figure 1 Anti-ERBB2 Recombinant Antibody (Margetuximab) (TAB-761) in SPR
SPR assays of TAB-761.
The affinity of Anti-ERBB2 Therapeutic Antibody (Margetuximab) (TAB-761) was determined by SPR.
Captured TAB-761 on CM5 Chip via Anti-Human IgG (Fc) can bind Human ERBB2 protein with an affinity constant of 1.21 nM as determined in a SPR assay (Biacore 8K).
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Chimeric (Human/Mouse)
- Type
- IgG1 - kappa
- Species Reactivity
- Human
- Applications
- Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
- CAS
- 1350624-75-7
- Generic Name
- margetuximab
- MW
- 145.9 kDa
- Related Disease
- Solid tumors
Product Property
- Purity
- >95%, by SDS-PAGE with silver staining, under reducing conditions.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- margetuximab;1350624-75-7;MGAH22;4D5;ERBB2;v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian);NGL, v erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived onco
- Gene ID
- 2064
- UniProt ID
- P04626
Related Resources
Please refer to Margetuximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Margetuximab.
Bladder Cancer
Non-small Cell Lung Cancer
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Margetuximab"
Afuco™ Anti-ERBB2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-761)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant chimeric (mouse/human) antibody expressed in CHO binding to human ERBB2. It is a monoclonal antibody designed for the treatment of cancer.
See other products for "ERBB2"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-059 | Recombinant Anti-Human ERBB2 VHH Single Domain Antibody | IHC, FC, CA, FuncS | Llama VHH |
| PNBL-066 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-066) | SPR | Llama VHH |
| PNBL-067 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-067) | SPR | Llama VHH |
| PNBL-069 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-069) | ELISA | Llama VHH |
| HPAB-0201-FY | Recombinant llama Anti-ERBB2 Antibody (HPAB-0201-FY) | E | llama VHH |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-761, RRID: AB_3112005)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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